Elevated basal activity of NF-κB in <i>Cyld^Δ9</i> BMDMs.

<p>A) EMSA of NF-κB DNA binding activity in BMDMs from control (<i>M-Cyld⁺</i>) and mutant (<i>M-Cyld^Δ9</i>) mice in the absence or presence of 100-fold excess of unlabeled probe (100× cold probe) as indicated. The positions of NF-κB-containing complexes of the radiolabeled probe are shown. B) Immunoblot of nuclear extracts used in A with an anti-TFIIB antibody. Three mice per genotype were evaluated.