<p>Non-synonymous mutations at nucleotides 223 and 317 are boxed; 10 synonymous mutations specific for the three core-antibody negative patients (p31, p32, p34) were observed. Nucleotide sequences were analyzed using the CLUSTAL W program.</p
<p>Variants are compared to consensus sequence for all sequences present in all patients. Silent and...
<p>The Greek numbers indicate how many nucleotides are called for the same positions where II, III, ...
How Hepatitis C Virus (HCV) causes persistent infection is unknown. One hypothesis is that HCV evade...
<p>cDNA fragments from the HCV core region were obtained and cloned into the TOPO TA vector as descr...
<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...
The biological role of the protein encoded by the alternative open reading frame (core+1/ARF) of the...
International audienceThe biological role of the protein encoded by the alternative open reading fra...
<p>Mutations were found by direct sequence analysis of RT-PCR from recovered viruses. Red columns de...
Genetic characterization of the genotype 3a (GT3a) hepatitis C virus (HCV) core region fromHCV core ...
<p>Numbers shown below the sequence represent the nucleotide position in the HCV complete genome. Th...
Objective: HCV is a single-stranded RNA virus which has 9500 nucleotide. On the 3’ and 5’ ends of th...
<p>Each line represents the core protein sequence of a strain (highlighted in gray) or a core protei...
A<p>Numbering is according to individual H77 reference proteins (AF009606). Numbering according to t...
<p>The sequences that correspond to the P4–P4′ positions are shown. Substitutions relative to the HC...
Hepatitis C virus (HCV) is a major health problem with a prevalence of 1% in the United States popul...
<p>Variants are compared to consensus sequence for all sequences present in all patients. Silent and...
<p>The Greek numbers indicate how many nucleotides are called for the same positions where II, III, ...
How Hepatitis C Virus (HCV) causes persistent infection is unknown. One hypothesis is that HCV evade...
<p>cDNA fragments from the HCV core region were obtained and cloned into the TOPO TA vector as descr...
<p>(A) Sequence alignment of region 313–327 from several HCV strains/isolates. (B) Sequence alignmen...
The biological role of the protein encoded by the alternative open reading frame (core+1/ARF) of the...
International audienceThe biological role of the protein encoded by the alternative open reading fra...
<p>Mutations were found by direct sequence analysis of RT-PCR from recovered viruses. Red columns de...
Genetic characterization of the genotype 3a (GT3a) hepatitis C virus (HCV) core region fromHCV core ...
<p>Numbers shown below the sequence represent the nucleotide position in the HCV complete genome. Th...
Objective: HCV is a single-stranded RNA virus which has 9500 nucleotide. On the 3’ and 5’ ends of th...
<p>Each line represents the core protein sequence of a strain (highlighted in gray) or a core protei...
A<p>Numbering is according to individual H77 reference proteins (AF009606). Numbering according to t...
<p>The sequences that correspond to the P4–P4′ positions are shown. Substitutions relative to the HC...
Hepatitis C virus (HCV) is a major health problem with a prevalence of 1% in the United States popul...
<p>Variants are compared to consensus sequence for all sequences present in all patients. Silent and...
<p>The Greek numbers indicate how many nucleotides are called for the same positions where II, III, ...
How Hepatitis C Virus (HCV) causes persistent infection is unknown. One hypothesis is that HCV evade...