<p>FACS plot of CD4<sup> +</sup> Foxp3<sup>+</sup> splenocytes (A) or CD4<sup> +</sup> Foxp3<sup>+</sup> MLN cells (B) are shown. Data shown are representative of 4 mice per group at either 2 or 10 months of age. WT = wildtype, L-<i>Tg</i> = <i>LCK-CD2-Tl1a-GFP Tg</i> mice, M-<i>Tg</i> = <i>FMS-Tl1a-GFP Tg</i> mice.</p
<p>(A and B) Lymphocyte (1×10<sup>6</sup>) isolated from CTB-GAD-, CTB-Ins-GAD-, CTB-GAD-Ins-, or WT...
<p>(<b>A</b>) Flow cytometry analysis of the percentage and number of PD-1<sup>+</sup>CXCR5<sup>+</s...
<p>(A-B) Flow cytometry profiles of (A) thymus and (B) spleen of <i>Usp21</i><sup>-/-</sup> and wild...
<p>(A and B) Age-associated increases in total CD4<sup>+</sup> T cell numbers in the spleen and PLN ...
<p>FACS plot of 2 month (A) and 10 month (B) splenocytes and MLN cells showing expression of activat...
(B) Frequency of CD4Foxp3 T reg cells expressing the indicated homing receptors in peripheral LNs (P...
<p>(A) Flow cytometry analysis with thymocytes from 6-week-old (w.o.) or 11 w.o. WT and LTAC mice. S...
<p>A. FoxP3 expression by CD4<sup>+</sup>CD8<sup>−</sup> thymocytes or CD4<sup>+</sup> cells from th...
<p>Spleens from naïve, 4-week-old WT (left panel) and p18<sup>ink4c</sup>−/− (right panel) mice were...
Abstract: A progressive decline in the integrity of the immune system is one of the physiologic chan...
<p>(A) T cell accumulation. LN cells were obtained from MRL-<i>Fas<sup>lpr</sup></i> and control C57...
<p>Young (2–4 mo old) or middle-aged (7–14 mo old) mice were sacrificed and spleen cell suspensions ...
Effector/memory T cells (Tem) are required to maintain successful immunity, while regulatory T cells...
<p>Single-cell suspensions of nucleated thymocytes from intact NIK KO or WT mice were stained with t...
<p>At the termination of 3 months treatment, female NZB/W F<sub>1</sub> mice in vehicle and SM934 (1...
<p>(A and B) Lymphocyte (1×10<sup>6</sup>) isolated from CTB-GAD-, CTB-Ins-GAD-, CTB-GAD-Ins-, or WT...
<p>(<b>A</b>) Flow cytometry analysis of the percentage and number of PD-1<sup>+</sup>CXCR5<sup>+</s...
<p>(A-B) Flow cytometry profiles of (A) thymus and (B) spleen of <i>Usp21</i><sup>-/-</sup> and wild...
<p>(A and B) Age-associated increases in total CD4<sup>+</sup> T cell numbers in the spleen and PLN ...
<p>FACS plot of 2 month (A) and 10 month (B) splenocytes and MLN cells showing expression of activat...
(B) Frequency of CD4Foxp3 T reg cells expressing the indicated homing receptors in peripheral LNs (P...
<p>(A) Flow cytometry analysis with thymocytes from 6-week-old (w.o.) or 11 w.o. WT and LTAC mice. S...
<p>A. FoxP3 expression by CD4<sup>+</sup>CD8<sup>−</sup> thymocytes or CD4<sup>+</sup> cells from th...
<p>Spleens from naïve, 4-week-old WT (left panel) and p18<sup>ink4c</sup>−/− (right panel) mice were...
Abstract: A progressive decline in the integrity of the immune system is one of the physiologic chan...
<p>(A) T cell accumulation. LN cells were obtained from MRL-<i>Fas<sup>lpr</sup></i> and control C57...
<p>Young (2–4 mo old) or middle-aged (7–14 mo old) mice were sacrificed and spleen cell suspensions ...
Effector/memory T cells (Tem) are required to maintain successful immunity, while regulatory T cells...
<p>Single-cell suspensions of nucleated thymocytes from intact NIK KO or WT mice were stained with t...
<p>At the termination of 3 months treatment, female NZB/W F<sub>1</sub> mice in vehicle and SM934 (1...
<p>(A and B) Lymphocyte (1×10<sup>6</sup>) isolated from CTB-GAD-, CTB-Ins-GAD-, CTB-GAD-Ins-, or WT...
<p>(<b>A</b>) Flow cytometry analysis of the percentage and number of PD-1<sup>+</sup>CXCR5<sup>+</s...
<p>(A-B) Flow cytometry profiles of (A) thymus and (B) spleen of <i>Usp21</i><sup>-/-</sup> and wild...