Effects of resveratrol and/or TRAIL on tumor cell proliferation and apoptosis.

<p>(A), Immunohistochemistry was performed in tumor tissues derived from control, resveratrol and/or TRAIL treated mice on week 6 to measure cell proliferation by Ki67 and PCNA staining and apoptosis by TUNEL assay. (B, C and D), Quantification of Ki67, PCNA and TUNEL positive tumor cells. Tumor slides of different treatment groups were visualized under microscope, and Ki67, PCNA and TUNEL positive cells were quantified. Data represent mean ± SE. * and ** are significantly different from their respective controls, P<0.05).