LVSCE/AMVAD vaccine partially protects against i.n. <i>F. tularensis</i> LVS challenge.

<p>The remaining naïve, and LVSCE, LVSCE/AMVAD or LVSCE/CT immunized groups of mice (n = 15) in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0015574#pone-0015574-g001" target="_blank">Figure 1</a> experiment, were intranasally challenged with <i>F. tularensis</i> LVS (3.4×10⁴ cfu) at 35 d (14 d post the last immunization). The % change in body weight (A), clinical scores (B) and % survival (C) of sub-groups of 5 mice per each group was recorded over a 22 d period subsequent to the challenge. The data are presented as mean ± SD for each group (n = 5) for panels A and B. ^**<i>p</i><0.01 vs. LVSCE alone immunized group. Data are representative of two separate experiments.