IKKβ was not required for LPS-induced mTORC1-S6K activation.
- Po-Shun Lee (358563)
- Anna S. K. Wilhelmson (358564)
- Anton P. Hubner (358566)
- Samuel B. Reynolds (358568)
- Dana A. Gallacchi (358571)
- Terry T. Chiou (358575)
- David J. Kwiatkowski (205391)
Publication date
February 2013
DOIAbstract
<p>IKKβ was suppressed in RAW cells by siRNA (IK) 48 hr prior to LPS stimulation. Nonsense siRNA constructs (NS) served as controls. Representative immunoblots show that IKKβ suppression had no effect on mTORC1-S6K activation in LPS-treated RAW cells as reflected by pS6 levels.</p
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