Zinc treatment enhances neuritic plaque formation in APP/PS1 mice.

<p>(<b>A</b>) Aβ immunohistochemical images showing the Aβ-positive plaques in the transgenic mouse brain. There were more neuritic plaques in Zn-treated mice compared with controls. (<b>B</b>) Quantification of neuritic plaques showed that both the number and size of neuritic plaques were increased in Zn-treated mice compared with controls. ** <i>p</i><0.01 versus control group (Student's <i>t</i> test).