<p>Corresponding low-power and high-power photomicrographs of NeuN-immunofluorescent stained horizontal sections of the hippocampus depicting surviving cells throughout the hippocampus 7 days following systemic KA administration to GalR1<sup>−/−</sup> and GalR1<sup>+/+</sup> mice. Hippocampal sections from GalR1<sup>+/+</sup> and GalR1<sup>−/−</sup> brains were stained with NeuN immunofluorescence to determine the amount of cellular damage. Note the massive loss of neurons, as evidenced by loss of immunostaining, in the hilar, CA3 and CA1 fields of the hippocampus, seven days after a systemic injection of KA inGalR1<sup>−/−</sup> mice. In contrast, hippocampal cell death was essentially non-existent throughout all hippocampal subfields in G...
<p>Anti-GFAP antibody (brown) and hematoxylin (blue) staining in A) whole brain and B) enlargement s...
<p>(<b>A</b>) Mouse survival was monitored for 24 hours after exposure of control (n = 8) and N<i>ca...
<p><b>A-C)</b> Fluoro-Jade C staining is observed 24h after IN KA, diminishing at 72h. Correspondenc...
<p>Corresponding low-power and high-power photomicrographs of NeuN- stained horizontal sections of t...
Galanin is a neuropeptide with a wide distribution in the central and peripheral nervous systems and...
Galanin is a neuropeptide with a wide distribution in the central and peripheral nervous systems and...
<p>Quantitative analysis of neuronal density in four hippocampal subfields following kainate-induced...
<p>Real-time PCR quantification of the levels of GalR1, GalR2, and galanin produced in the hippocamp...
Restricted until 25 March 2009.Glutamate excitotoxicity plays a role in neuronal death in diverse ne...
<p>Quantitative analysis of neuron density in the dentate hilus, areas CA3 and CA1, and dentate gyru...
<p>(A) Data represent latency to severe stage 4/5 seizures in minutes (mean ± SEM) for GalR1 <sup>+/...
<p>(A) Representative FJB and TUNEL staining for wt and 14-3-3ζtg mice 72 h after status epilepticus...
Mesial temporal lobe epilepsy is the most common, intractable seizure disorder in adults. It is asso...
<p>Immunohistochemistry for GFAP (red) and Thioflavine-S (green) in the hippocampi (A) and the corti...
<p>(A-C) In saline-injected control mice (n = 4), the density of pS6 IR varies in the different hipp...
<p>Anti-GFAP antibody (brown) and hematoxylin (blue) staining in A) whole brain and B) enlargement s...
<p>(<b>A</b>) Mouse survival was monitored for 24 hours after exposure of control (n = 8) and N<i>ca...
<p><b>A-C)</b> Fluoro-Jade C staining is observed 24h after IN KA, diminishing at 72h. Correspondenc...
<p>Corresponding low-power and high-power photomicrographs of NeuN- stained horizontal sections of t...
Galanin is a neuropeptide with a wide distribution in the central and peripheral nervous systems and...
Galanin is a neuropeptide with a wide distribution in the central and peripheral nervous systems and...
<p>Quantitative analysis of neuronal density in four hippocampal subfields following kainate-induced...
<p>Real-time PCR quantification of the levels of GalR1, GalR2, and galanin produced in the hippocamp...
Restricted until 25 March 2009.Glutamate excitotoxicity plays a role in neuronal death in diverse ne...
<p>Quantitative analysis of neuron density in the dentate hilus, areas CA3 and CA1, and dentate gyru...
<p>(A) Data represent latency to severe stage 4/5 seizures in minutes (mean ± SEM) for GalR1 <sup>+/...
<p>(A) Representative FJB and TUNEL staining for wt and 14-3-3ζtg mice 72 h after status epilepticus...
Mesial temporal lobe epilepsy is the most common, intractable seizure disorder in adults. It is asso...
<p>Immunohistochemistry for GFAP (red) and Thioflavine-S (green) in the hippocampi (A) and the corti...
<p>(A-C) In saline-injected control mice (n = 4), the density of pS6 IR varies in the different hipp...
<p>Anti-GFAP antibody (brown) and hematoxylin (blue) staining in A) whole brain and B) enlargement s...
<p>(<b>A</b>) Mouse survival was monitored for 24 hours after exposure of control (n = 8) and N<i>ca...
<p><b>A-C)</b> Fluoro-Jade C staining is observed 24h after IN KA, diminishing at 72h. Correspondenc...