Sparse network reconstruction among 35 gene expression products.

<p>These genes were filtered for having strong, independent <i>cis</i>-eQTL (pairwise ) using the adaptive lasso algorithm for a <i>Saccharomyces cerevisiae</i> cross between a wild strain and lab strain <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1001014#pcbi.1001014-Stranger1" target="_blank">[27]</a>, with 112 segregants (see text for details). (a) Recovered undirected network among these 35 gene expression products and (b) putative directed network reconstructed for the same genes, based on the edges between <i>cis</i>-eQTL (not shown) and the 35 genes. Bold edges represent directed edges with strong confidence based on a resampling procedure (see text for details).