Hsc70 is detected in virus-induced chaperone-enriched (VICE) domains that form adjacent to replication compartments in HSV-1-infected cells.

<p>Vero cells were infected with HSV-1 strain KOS at an MOI of 10 for 6 hours. Infected cells were prepared for immunofluorescence imaging of ICP8 in red (left), Hsc70 in green (center), and a merged image (right) as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1001105#ppat.1001105-Livingston2" target="_blank">[24]</a>.