<p><i>Il17ra<sup>−/−</sup></i> mice, <i>Il17ra<sup>+/−</sup></i> littermates and C57BL/6 control mice were pretreated with streptomycin and infected for 12 hours with <i>S</i>.Tm* or isogenic derivatives <i>S</i>.Tm<sup>SipA</sup>, <i>S</i>.Tm<sup>SopE</sup>, <i>S</i>.Tm<sup>avir</sup> (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013804#s2" target="_blank">Material and Methods</a>). We analyzed colonization levels in the gut lumen (A) and the mLN (B), as well as the degree of inflammation of the cecum mucosa (C). n.s.: No significant difference between <i>Il17ra<sup>−/−</sup></i> mice and <i>Il17ra<sup>+/−</sup></i> littermates. Strippled line: minimal detectable value.</p
International audienceSalmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium) causes d...
<p>Groups of streptomycin pre-treated mice (<i>N</i> is indicated below the graph in panel A) were i...
<p>(A) <i>Il17a</i>, <i>Il17f</i> and <i>Il17ra</i> expression in the intestinal tissues of naïve mi...
<p>Streptomycin treated mice were infected with wild type <i>S</i>. Typhimurium cultured to mid-loga...
<p>C57BL/6 mice were vaccinated three times (50 µg each, s.c.) with IL-17A-VLP, IL-17F-VLP, either r...
<p>Number of viable bacteria in total (<b>A</b>) small intestine and (<b>B</b>) colon at day 1 and 2...
<p>Streptomycin-pretreated C57Bl/6 and <i>Nod2<sup>−/−</sup></i> mice were orally infected with wild...
<p>(A and B) Groups of 8–10-week-old, streptomycin-pretreated Lcn2<sup>−/−</sup> mice were mock (Con...
<p>(A) Scatter plot demonstrating depletion of colonic IL-1R1<sup>+</sup> CD4<sup>+</sup> Lin<sup>−<...
<p>(A) <i>Sigirr −/−</i> mice were heavily colonized by 100× lower dose (LD) of <i>C. rodentium</i> ...
<p>A) Mice were co-infected with 10<sup>8</sup> SL1344 orally and 10<sup>3</sup> SL1344-<i>kan<sup>R...
<p>(a) Mature IL-1β and IL-18 protein levels were measured in whole cecum tissue homogenates from C5...
<p>WT, p19<sup>−/−</sup>(no IL-23), p35<sup>−/−</sup>(no IL-12), and p40<sup>−/−</sup> (no IL-12/-23...
<p>IL-17RA−/− mice, IL-17RB−/− mice and WT mice were infected with <i>H. pylori</i> strain SS1. Leve...
<p><i>Cybb</i><sup>−/−</sup><i>Myd88</i><sup>+/−</sup> mice or C<i>ybb</i><sup>−/−</sup><i>Myd88</i>...
International audienceSalmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium) causes d...
<p>Groups of streptomycin pre-treated mice (<i>N</i> is indicated below the graph in panel A) were i...
<p>(A) <i>Il17a</i>, <i>Il17f</i> and <i>Il17ra</i> expression in the intestinal tissues of naïve mi...
<p>Streptomycin treated mice were infected with wild type <i>S</i>. Typhimurium cultured to mid-loga...
<p>C57BL/6 mice were vaccinated three times (50 µg each, s.c.) with IL-17A-VLP, IL-17F-VLP, either r...
<p>Number of viable bacteria in total (<b>A</b>) small intestine and (<b>B</b>) colon at day 1 and 2...
<p>Streptomycin-pretreated C57Bl/6 and <i>Nod2<sup>−/−</sup></i> mice were orally infected with wild...
<p>(A and B) Groups of 8–10-week-old, streptomycin-pretreated Lcn2<sup>−/−</sup> mice were mock (Con...
<p>(A) Scatter plot demonstrating depletion of colonic IL-1R1<sup>+</sup> CD4<sup>+</sup> Lin<sup>−<...
<p>(A) <i>Sigirr −/−</i> mice were heavily colonized by 100× lower dose (LD) of <i>C. rodentium</i> ...
<p>A) Mice were co-infected with 10<sup>8</sup> SL1344 orally and 10<sup>3</sup> SL1344-<i>kan<sup>R...
<p>(a) Mature IL-1β and IL-18 protein levels were measured in whole cecum tissue homogenates from C5...
<p>WT, p19<sup>−/−</sup>(no IL-23), p35<sup>−/−</sup>(no IL-12), and p40<sup>−/−</sup> (no IL-12/-23...
<p>IL-17RA−/− mice, IL-17RB−/− mice and WT mice were infected with <i>H. pylori</i> strain SS1. Leve...
<p><i>Cybb</i><sup>−/−</sup><i>Myd88</i><sup>+/−</sup> mice or C<i>ybb</i><sup>−/−</sup><i>Myd88</i>...
International audienceSalmonella enterica subspecies 1 serovar Typhimurium (S. Typhimurium) causes d...
<p>Groups of streptomycin pre-treated mice (<i>N</i> is indicated below the graph in panel A) were i...
<p>(A) <i>Il17a</i>, <i>Il17f</i> and <i>Il17ra</i> expression in the intestinal tissues of naïve mi...