<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for another 180 min with Pam<sub>3</sub>Cys (160 ng/mL, n = 5), MALP-2 (25 ng/mL, n = 5), LPS (1 µg/mL, n = 3) or under control conditions (n = 5). Genes: interleukin 4 (Il4), interleukin 12p35 (Il12a), tenascin C (Tnc), interleukin 10 (Il10), cyclooxygenase 2 (<i>Ptgs2</i>), and IP10 (<i>Cxcl10</i>). Data were normalized to the experimental control and are shown as mean ± SEM. *, p<0.05 vs control; **, p<0.01 vs control; ***, p<0.001 vs control.</p
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>(A) Relative <i>Arg1</i> mRNA expression was significantly higher in the control + LPS group than...
<p>C57BL/6 and GKO mice were infected as indicated in the legend to <a href="http://www.plosone.org/...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>(A) Fold changes in gene expression of both unprotected and protected mice were calculated compar...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>The expression of IFN-γ, TNF-α, IL-4, IL-6, IL-10, IL-12p40, IL-17, and IL-23p19 in the lungs of ...
<p>WT (black bars) and MyD88<sup>−/−</sup> mice (white bars) were inoculated intranasally with PBS (...
<p>Hierarchical cluster analyses of 57 DEG between PM2.5win-treated lung (n = 5) and sham (n = 5) mi...
<p>(A) The protein levels of cytokines IL-1β, IL-6, RANTES and IL-10 presented in mouse lung homogen...
<p>A) Fold change of genes related to chemoattractants to Th1, Th2, Th17 and ...
<p>A: Peribronchial and interstitial inflammation was scored from 0–4 as described in methods. Data ...
Microarray gene expression profiling identified a set of 119 genes whose expression changed signific...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>(A) Relative <i>Arg1</i> mRNA expression was significantly higher in the control + LPS group than...
<p>C57BL/6 and GKO mice were infected as indicated in the legend to <a href="http://www.plosone.org/...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>(A) Fold changes in gene expression of both unprotected and protected mice were calculated compar...
<p>After 60 min of perfusion under baseline conditions, isolated mouse lungs were perfused for anoth...
<p>The expression of IFN-γ, TNF-α, IL-4, IL-6, IL-10, IL-12p40, IL-17, and IL-23p19 in the lungs of ...
<p>WT (black bars) and MyD88<sup>−/−</sup> mice (white bars) were inoculated intranasally with PBS (...
<p>Hierarchical cluster analyses of 57 DEG between PM2.5win-treated lung (n = 5) and sham (n = 5) mi...
<p>(A) The protein levels of cytokines IL-1β, IL-6, RANTES and IL-10 presented in mouse lung homogen...
<p>A) Fold change of genes related to chemoattractants to Th1, Th2, Th17 and ...
<p>A: Peribronchial and interstitial inflammation was scored from 0–4 as described in methods. Data ...
Microarray gene expression profiling identified a set of 119 genes whose expression changed signific...
<p>Mice (n = 12/group) were infected i.n. with 10<sup>4</sup> PFU of V<sub>K627</sub> (▪), rV<sub>K6...
<p>(A) Relative <i>Arg1</i> mRNA expression was significantly higher in the control + LPS group than...
<p>C57BL/6 and GKO mice were infected as indicated in the legend to <a href="http://www.plosone.org/...