<p>PET blots show prominent deposition of PrP<sup>Sc</sup> in granular and molecular cell layers in clinically diseased vCJD and BSE inoculated animals whereas the subclinical vCJD inoculated primate only shows faint PrP<sup>Sc</sup> in granular and molecular cell layers (scale bar in lower left image 1 mm).</p
Introduction: It has been previously reported that the same `prion strain' causes vCJD and BSE [Hill...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
<p>A) Western Blot analysis for PrP<sup>Sc</sup> (frontal cortex) of vCJD, BSE and sCJD infected ani...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 Mab. Similar quantities of PrP<sup>re...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 and 12B2 mAbs. Similar quantities of ...
<p>a) VRQ/VRQ sheep showing diffuse particulate and stellate types of PrP<sup>d</sup> accumulation i...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 Mab. Similar amount of brain tissue e...
<p>(A) 40 dpi. (B) 60 dpi. On each western blot, two representative thalamus samples are shown for e...
<p>A) Western Blot analysis of PrP<sup>Sc</sup> from NaPTA precipitated arm and tongue tissue of sCJ...
<p>(<b>A</b>) Samples from five brain regions of calf #83 demonstrate the characteristic 3-band prof...
<p>The main type of PrP<sup>d</sup> deposition was granular (A–H), and within the cytoplasm of neuro...
<p>Representative PET-blot results from macaque B3 that was euthanized 4.3 years after oral BSE upta...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
(A) Western blot analysis. Homogenates of bovine and monkey brains were digested by PK, and subjecte...
Introduction: It has been previously reported that the same `prion strain' causes vCJD and BSE [Hill...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
<p>A) Western Blot analysis for PrP<sup>Sc</sup> (frontal cortex) of vCJD, BSE and sCJD infected ani...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 Mab. Similar quantities of PrP<sup>re...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 and 12B2 mAbs. Similar quantities of ...
<p>a) VRQ/VRQ sheep showing diffuse particulate and stellate types of PrP<sup>d</sup> accumulation i...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 Mab. Similar amount of brain tissue e...
<p>(A) 40 dpi. (B) 60 dpi. On each western blot, two representative thalamus samples are shown for e...
<p>A) Western Blot analysis of PrP<sup>Sc</sup> from NaPTA precipitated arm and tongue tissue of sCJ...
<p>(<b>A</b>) Samples from five brain regions of calf #83 demonstrate the characteristic 3-band prof...
<p>The main type of PrP<sup>d</sup> deposition was granular (A–H), and within the cytoplasm of neuro...
<p>Representative PET-blot results from macaque B3 that was euthanized 4.3 years after oral BSE upta...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
(A) Western blot analysis. Homogenates of bovine and monkey brains were digested by PK, and subjecte...
Introduction: It has been previously reported that the same `prion strain' causes vCJD and BSE [Hill...
<p>(<b>A</b>) First column: Paraffin-embedded tissue (PET) blots demonstrating PrP<sup>Sc</sup> depo...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...