<p>A. Virus titers in lung homogenates collected from mice infected with wild type (WT) or mutant (Mut) virus on indicated days post-infection were measured by plaque forming assay. ** indicates significant differences (<i>P</i><0.001) between pregnant and non-pregnant mice. B. Viral RNA copies in the same lung homogenates were also determined by real-time RT-PCR. * indicates significant differences (<i>P</i><0.001) between pregnant and non-pregnant mice. C. Immunohistochemical staining for influenza viral nucleoprotein (NP) protein in lung sections of infected mice. Representative images of lung sections from wild type virus infected bronchial epithelium of non-pregnant (a) and pregnant (b) mice, and mutant virus infected alveoli of non-pr...
<p>16-week-old BALB/c mice were inoculated intranasally with 100,000 pfu of wt, ΔE, ΔPBM, mutPBM and...
<p>Groups of 4 CD-1 mice were infected with 1×10<sup>5</sup> PFU dose of selected rHK NS mutant or r...
<p>Bronchoalveolar lavage was taken from six to nine week old DBA/2 mice that were infected with 10<...
<p>A. Representative images of immunohistochemically stained influenza nucleoprotein (NP) in formali...
<p>A. Lungs from mock infected (a, d) and infected (b, c, e, f) pregnant and non-pregnant mice were ...
<p>A) Immunohistochemistry of influenza-infected lungs. Paraffin embedded sections of mouse lungs we...
<p>Virus titers in the lung tissues were determined by TCID<sub>50</sub> in the MDCK cell line at 3 ...
<p>Lung samples of M and F virus-infected mice were used for histopathological H&E examination at th...
<p>Female BALB/c mice were infected intranasally with 10<sup>2</sup> PFU of influenza viruses and lu...
(A) Mice were infected i.n. with H3N2 virus. The frequency (left panel) and absolute number (right p...
<p>Proinflammatory cytokines and chemokines in lung homogenates collected from wild type (WT) or mut...
The pathogenesis of pneumonia virus of mice (PVM) and human respiratory syncytial virus (HRSV) in BA...
<p>BALB/c mice were infected with wild-type virus and three days later, their lungs were dissected o...
<p>C57BL/6 mice were inoculated i.n. with 1x 10<sup>3</sup> PFU of the indicated viruses. Lungs of m...
<p>Two weeks after the boost, vaccinated mice were i.n. infected with Ah01/H7N9 (50LD<sub>50</sub>) ...
<p>16-week-old BALB/c mice were inoculated intranasally with 100,000 pfu of wt, ΔE, ΔPBM, mutPBM and...
<p>Groups of 4 CD-1 mice were infected with 1×10<sup>5</sup> PFU dose of selected rHK NS mutant or r...
<p>Bronchoalveolar lavage was taken from six to nine week old DBA/2 mice that were infected with 10<...
<p>A. Representative images of immunohistochemically stained influenza nucleoprotein (NP) in formali...
<p>A. Lungs from mock infected (a, d) and infected (b, c, e, f) pregnant and non-pregnant mice were ...
<p>A) Immunohistochemistry of influenza-infected lungs. Paraffin embedded sections of mouse lungs we...
<p>Virus titers in the lung tissues were determined by TCID<sub>50</sub> in the MDCK cell line at 3 ...
<p>Lung samples of M and F virus-infected mice were used for histopathological H&E examination at th...
<p>Female BALB/c mice were infected intranasally with 10<sup>2</sup> PFU of influenza viruses and lu...
(A) Mice were infected i.n. with H3N2 virus. The frequency (left panel) and absolute number (right p...
<p>Proinflammatory cytokines and chemokines in lung homogenates collected from wild type (WT) or mut...
The pathogenesis of pneumonia virus of mice (PVM) and human respiratory syncytial virus (HRSV) in BA...
<p>BALB/c mice were infected with wild-type virus and three days later, their lungs were dissected o...
<p>C57BL/6 mice were inoculated i.n. with 1x 10<sup>3</sup> PFU of the indicated viruses. Lungs of m...
<p>Two weeks after the boost, vaccinated mice were i.n. infected with Ah01/H7N9 (50LD<sub>50</sub>) ...
<p>16-week-old BALB/c mice were inoculated intranasally with 100,000 pfu of wt, ΔE, ΔPBM, mutPBM and...
<p>Groups of 4 CD-1 mice were infected with 1×10<sup>5</sup> PFU dose of selected rHK NS mutant or r...
<p>Bronchoalveolar lavage was taken from six to nine week old DBA/2 mice that were infected with 10<...