UCP2 knockdown enhanced p53 mitochondrial translocation and decreased colony formation in response to TPA treatment.
- Fei Wang (19534)
- Xueqi Fu (333099)
- Xia Chen (299366)
- Xinbin Chen (196609)
- Yunfeng Zhao (244764)
Publication date
February 2013
DOIAbstract
<p>(A) UCP2 knockdown efficiency examined by Western blot analysis. (B) p53 mitochondrial translocation. (C) Soft agar colony formation assays of JB6 P+ cells (light micrograph: 100× magnification). (D) Quantification of formed colonies. Cells grown in 0.33% soft agar containing 6.66 ng/ml TPA or vehicle (DMSO 1000× diluted). *: Significant difference compared to DMSO treatment. **: Significant difference compared to normal cells with TPA treatment.</p
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