<p>The neutralizing activity was determined using the mouse protection assay with 5 estimated MLD<sub>50</sub>/mouse of BoN/A1. BoNT/A1 (0.5 ml) and serial dilutions of cTA12 (0.5 ml) were injected separately into each mouse of a group of 8–10. Results are expressed as surviving mice versus the total number of mice.</p
<p>ID<sub>50</sub> neutralizing antibody assays were carried out on sera of mice that were injected ...
B10.D2/nSnJ (-sufficient) mice that received anti-C5aR serum ( = 8) were significantly protected fro...
<p><b>(A)</b> Scheme of immunotherapy experiments. C57BL/6 mice were infected and treated with an an...
<p>MAb protection activity was determined using the mouse protection assay with 5 estimated MLD<sub>...
<p>50 µg of purified antibody was intraperitoneally injected into Swiss mice (n = 3 or 4). Mice were...
<p>A constant dilution of individual MAb ascitesfluids (1∶100) was pre-incubated with different toxi...
(A) Mouse survival curve following IP injection of 1ng and 2.5ng TcsL. (B) Mouse survival curve foll...
<p><b><i>A)</i></b> Neutralization Canonical pair <b><i>B)</i></b> Neutralization of noncanonical pa...
<p>Two-day-old suckling mice (ICR strain) were injected intracranially (i.c.) with 1×10<sup>4</sup> ...
<p>A129 mice (n = 6) were challenged with double the minimum lethal dose of CCHFv 14 days after boos...
<p>The 6A and 4LCA mAbs were tested in un-modified and biotinylated ...
<p>Appropriately diluted viruses were mixed at indicated dilutions with the serum (A), TW (B), or NW...
<p>BoNT/A (10 LD50) was administered via intra-peritoneal injection to Swiss ...
<p>(A) Each group of mice (n = 5) was immunized by IM-EP with 50 µg of E7 DNA vaccines (pE7) at 0 an...
<p>Percentage ratio between withdrawal thresholds of hindpaws in naïve (○) mice and between withdraw...
<p>ID<sub>50</sub> neutralizing antibody assays were carried out on sera of mice that were injected ...
B10.D2/nSnJ (-sufficient) mice that received anti-C5aR serum ( = 8) were significantly protected fro...
<p><b>(A)</b> Scheme of immunotherapy experiments. C57BL/6 mice were infected and treated with an an...
<p>MAb protection activity was determined using the mouse protection assay with 5 estimated MLD<sub>...
<p>50 µg of purified antibody was intraperitoneally injected into Swiss mice (n = 3 or 4). Mice were...
<p>A constant dilution of individual MAb ascitesfluids (1∶100) was pre-incubated with different toxi...
(A) Mouse survival curve following IP injection of 1ng and 2.5ng TcsL. (B) Mouse survival curve foll...
<p><b><i>A)</i></b> Neutralization Canonical pair <b><i>B)</i></b> Neutralization of noncanonical pa...
<p>Two-day-old suckling mice (ICR strain) were injected intracranially (i.c.) with 1×10<sup>4</sup> ...
<p>A129 mice (n = 6) were challenged with double the minimum lethal dose of CCHFv 14 days after boos...
<p>The 6A and 4LCA mAbs were tested in un-modified and biotinylated ...
<p>Appropriately diluted viruses were mixed at indicated dilutions with the serum (A), TW (B), or NW...
<p>BoNT/A (10 LD50) was administered via intra-peritoneal injection to Swiss ...
<p>(A) Each group of mice (n = 5) was immunized by IM-EP with 50 µg of E7 DNA vaccines (pE7) at 0 an...
<p>Percentage ratio between withdrawal thresholds of hindpaws in naïve (○) mice and between withdraw...
<p>ID<sub>50</sub> neutralizing antibody assays were carried out on sera of mice that were injected ...
B10.D2/nSnJ (-sufficient) mice that received anti-C5aR serum ( = 8) were significantly protected fro...
<p><b>(A)</b> Scheme of immunotherapy experiments. C57BL/6 mice were infected and treated with an an...