Copy number of <i>FCGR3B</i> gene in RA patients versus healthy controls.

<p>The normalized MLPA ratios measured with FCGR3B#1, FCGR3B#2 and FCGR3B#3 probe-sets are plotted for RA patients and healthy controls. Three genes <i>EXT1</i>, <i>CREBBP</i> and <i>EP300</i> were used as reference for normalization (2 copies without CNV) and are shown here for all individuals. The clusters reflecting the copy numbers are illustrated by grey ovals. FCGR3B#1 and FCGR3B#2 showed clear clusters and copy numbers could be assigned, while FCGR3B#3 showed no CNV.