<p>IFN-γ resistant cells were transfected separately with the respective STAT1 plasmid and treated with or without IFN-γ. At 72 hours the cells were mounted onto a glass slide, stained for with DAB for HCV NS3 (brown), and counterstained with hematoxylin (blue). Huh7 cells without virus were used as a negative control.</p
<p>(A) HuH7 cells were mock-transfected (lane 1) or transfected with empty vector (3 ug, lane 2), th...
<p>Cells were treated with 0–10<sup>4</sup> IU/mL IFN-α for 72 h. HCV RNA was measured by rqRT-PCR a...
<p>(A) Huh7 cells transfected with pEF (empty vector), pHA-F, pFLAG-NS3/4A, or pHA-F plus pFLAG-NS3/...
<p>Stable sensitive (S5-15) and resistant (GR17-1) cell lines with or without STAT1 or STAT1-CC were...
<p>IFN-γ resistant (GR17-1) cells were transfected with the respective plasmid and treated with or w...
<p><b>(A)</b> Persistently infected HCV (JFH1ΔV3-Rluc) cultures were treated with equivalent concent...
<p>(<b>A</b>) The GAS-luciferase activity in the sensitive and resistant replicons. One sensitive an...
<p>(A) HCV replicon cells were transfected with empty vector (lane 2) or the plasmid expressing cdN ...
<div><p>Background</p><p>HCV replication in persistently infected cell culture remains resistant to ...
<p>(<b>A</b>) S3-GFP cells were treated with IFN-α and RBV for 72 hours. GFP expression was examined...
Background HCV replication in persistently infected cell culture remains resistant to IFN-α/RBV comb...
<p>(A) Huh7.5 cells were mock transfected or transfected with SGR, Jc1 or Jc1ΔGDD (ΔGDD) RNA, co-cul...
<p>(A) Verification of IFN-α resistance of the mutant HCV. Huh7.5 cells were infected with either ad...
<p><i>A</i>, Enhanced infection of SeV by neutralization of constitutive IFN-α visualized with IF. C...
<p>The IFN-γ resistant cell line (GR17-1) was transfected with each STAT1 expression plasmid and tre...
<p>(A) HuH7 cells were mock-transfected (lane 1) or transfected with empty vector (3 ug, lane 2), th...
<p>Cells were treated with 0–10<sup>4</sup> IU/mL IFN-α for 72 h. HCV RNA was measured by rqRT-PCR a...
<p>(A) Huh7 cells transfected with pEF (empty vector), pHA-F, pFLAG-NS3/4A, or pHA-F plus pFLAG-NS3/...
<p>Stable sensitive (S5-15) and resistant (GR17-1) cell lines with or without STAT1 or STAT1-CC were...
<p>IFN-γ resistant (GR17-1) cells were transfected with the respective plasmid and treated with or w...
<p><b>(A)</b> Persistently infected HCV (JFH1ΔV3-Rluc) cultures were treated with equivalent concent...
<p>(<b>A</b>) The GAS-luciferase activity in the sensitive and resistant replicons. One sensitive an...
<p>(A) HCV replicon cells were transfected with empty vector (lane 2) or the plasmid expressing cdN ...
<div><p>Background</p><p>HCV replication in persistently infected cell culture remains resistant to ...
<p>(<b>A</b>) S3-GFP cells were treated with IFN-α and RBV for 72 hours. GFP expression was examined...
Background HCV replication in persistently infected cell culture remains resistant to IFN-α/RBV comb...
<p>(A) Huh7.5 cells were mock transfected or transfected with SGR, Jc1 or Jc1ΔGDD (ΔGDD) RNA, co-cul...
<p>(A) Verification of IFN-α resistance of the mutant HCV. Huh7.5 cells were infected with either ad...
<p><i>A</i>, Enhanced infection of SeV by neutralization of constitutive IFN-α visualized with IF. C...
<p>The IFN-γ resistant cell line (GR17-1) was transfected with each STAT1 expression plasmid and tre...
<p>(A) HuH7 cells were mock-transfected (lane 1) or transfected with empty vector (3 ug, lane 2), th...
<p>Cells were treated with 0–10<sup>4</sup> IU/mL IFN-α for 72 h. HCV RNA was measured by rqRT-PCR a...
<p>(A) Huh7 cells transfected with pEF (empty vector), pHA-F, pFLAG-NS3/4A, or pHA-F plus pFLAG-NS3/...