miR-103 is directly involved in IGF-1 stimulated crypt cell proliferation.

<p>IEC-6 cells in 96-well plate were transfected with 50 nM miR-103 mimic before treated with 20 ng/ml IGF-1. The control group was cultured in growth media or treated with IGF-1 alone. Cell proliferation was measured by BrdU incorporation assay. Values are means ± SEM run in triplicates. Letters indicate significant differences between IGF-1 treatment and control groups.