TGFβ1 suppresses expression and release of markers of decidualization by cells from 1^st trimester decidua.

<p>A: TGFβ1 reduced expression of IGFBP-1 mRNA after 72 h treatment. (p<0.05) 1.0 = absolute value of ΔCT = 12.2. B: TGFβ1 was without significant effect on protein release of IGFBP-1. C: TGFβ1 reduced expression of PRL mRNA after 72 h treatment (p<0.001). 1.0 = absolute value of ΔCT = 11.5. D: TGFβ1 was without significant effect on PRL protein release, although did display a trend toward inhibition. E: TGFβ1 reduced expression of TF mRNA after 72 h treatment (p<0.05). 1.0 = absolute value of ΔCT = 13.75. Data are mean ± S.E.M; * p<0.05, *** p<0.001 vs. no TGFβ1 treatment. n = 7 decidual samples (in triplicate).