<p>Representative examples of kidney sections stained with PAS in 400x for all the samples are shown. (A) Non transgenic mouse normal glomerulus, (B) Trpc6-HA wt line 419, (C) Trpc6-HA wt line 421, (D) Trpc6-HA P111Q line 615, (E) Trpc6-HA P111Q line 616, (F) Trpc6-HA E896K line 73a and (G) Trpc6-HA E896K line 75a. The glomerular lesions were analyzed in blind by a pathologist and are summarized in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0012859#pone-0012859-t001" target="_blank">Table 1</a>.</p
<p>(A) At the end of the treatment period (8 weeks), kidney tissues from mice (starting at 12 weeks ...
<p>(A) Histological examinations with regard to renal injury revealed no significant differences bet...
<p>Hematoxylin and eosin-stained tissues from kidneys of age-matched adult mice are shown. All kidne...
<p>Hematoxylin/eosine staining. Analysis were done in wild‐type mice (row A), single mutants (row B)...
<p>The kidney sections were stained with hematoxylin and eosin (H&E) and representative images are s...
<p>(<b>A,B,G</b>) Representative H&E (A: Ad-RGD-CMV-GFP, B: Ad-RGD-CYP-GFP) and Jones (G: Ad-RGD-CMV...
<p>Albuminuria levels (µg/dL) normalized by creatininuria levels (mg/dL) were tested in male mice at...
<p>(A) Representative images of paraffin kidney sections stained with HE in control (CTL) and <i>Ppa...
<p>Representative images in <i>Trpv5<sup>+/+</sup></i> (wt), <i>Trpv5<sup>682P/+</sup></i> (het) and...
<p>(A–C) H&E staining showing: (A) small size and grossly abnormal morphology of RENF kidneys (scale...
<p>(A) PAS-stained kidney sections at 8 days, 3 months, 6 months and 12 months of age in ht (upper p...
<p>Anatomical analysis of pGtoR integrated adult (18 months old) Inv-KD mice (b and c) and control l...
<p>Kidney sections from 3 month old non transgenic (top panel) and transgenic (bottom panel) mice we...
<p>Paraffin-embedded PFA fixed-kidney sections were stained with periodic-acid Schiff. (A) Represent...
<p><b>Panels A-F: High power images of typical glomeruli stained with periodic acid-Schiff (PAS).</b...
<p>(A) At the end of the treatment period (8 weeks), kidney tissues from mice (starting at 12 weeks ...
<p>(A) Histological examinations with regard to renal injury revealed no significant differences bet...
<p>Hematoxylin and eosin-stained tissues from kidneys of age-matched adult mice are shown. All kidne...
<p>Hematoxylin/eosine staining. Analysis were done in wild‐type mice (row A), single mutants (row B)...
<p>The kidney sections were stained with hematoxylin and eosin (H&E) and representative images are s...
<p>(<b>A,B,G</b>) Representative H&E (A: Ad-RGD-CMV-GFP, B: Ad-RGD-CYP-GFP) and Jones (G: Ad-RGD-CMV...
<p>Albuminuria levels (µg/dL) normalized by creatininuria levels (mg/dL) were tested in male mice at...
<p>(A) Representative images of paraffin kidney sections stained with HE in control (CTL) and <i>Ppa...
<p>Representative images in <i>Trpv5<sup>+/+</sup></i> (wt), <i>Trpv5<sup>682P/+</sup></i> (het) and...
<p>(A–C) H&E staining showing: (A) small size and grossly abnormal morphology of RENF kidneys (scale...
<p>(A) PAS-stained kidney sections at 8 days, 3 months, 6 months and 12 months of age in ht (upper p...
<p>Anatomical analysis of pGtoR integrated adult (18 months old) Inv-KD mice (b and c) and control l...
<p>Kidney sections from 3 month old non transgenic (top panel) and transgenic (bottom panel) mice we...
<p>Paraffin-embedded PFA fixed-kidney sections were stained with periodic-acid Schiff. (A) Represent...
<p><b>Panels A-F: High power images of typical glomeruli stained with periodic acid-Schiff (PAS).</b...
<p>(A) At the end of the treatment period (8 weeks), kidney tissues from mice (starting at 12 weeks ...
<p>(A) Histological examinations with regard to renal injury revealed no significant differences bet...
<p>Hematoxylin and eosin-stained tissues from kidneys of age-matched adult mice are shown. All kidne...