Association between antibiotic resistance and inactivation of <i>mucA</i>, <i>lasR</i> and <i>mexZ.</i>

<p>(A) Differences in antibiotic resistance in the <i>P. aeruginosa</i> isolates harboring mutations in <i>mucA</i> (mucA-) respect to those without mutations in <i>mucA</i> (mucA+). Data is expressed as the percentage of resistant isolates to ceftazidime, ciprofloxacin, imipenem, meropenem and tobramycin in mucA- and mucA+ isolates. (B) The same analysis was carried out in lasR- and lasR+ isolates and (C) mexZ- and mexZ+ isolates. In the three genes, the observed differences were not significant (Fisher's exact test) for any of the tested antibiotics.