Acute effect of orally administered SSR240612 on systolic blood pressure in 12-week glucose-fed rats.

<p>Doses of 10 mg/kg and 30 mg/kg of SSR240612 were given to control rats and doses of 3, 10, 30 mg/kg of SSR240612 or vehicle were given to glucose-fed rats. Data are mean ± s.e.m of values obtained from (n) rats and represent changes of systolic blood pressure in mmHg (A) or Area Under the Curve (B). Statistical comparison with vehicle (V) in glucose-fed rats (+) is indicated by + P< 0.05.