<p>DAB staining of representative coronal CA1 sections show NSC23766 ability to attenuate staining for oxidative stress markers for lipid peroxidation (4-HNE), DNA damage (8-OHdG) and histone phosphorylation (p-H2A.X). (Four to five animals per treatment group, magnification used was 20X).</p
<p>8-OHDG levels in cortex and hippocampus of <i>gp91phox</i><sup>_<i>/Y</i></sup> and C57BL6/J mice...
The aim of this study was to clarify the relationship among Rac1 expression and activation, oxidativ...
PurposeThe active form of small GTPase RAC1 is required for activation of NADPH oxidase (NOX), which...
<p>NSC23766 pre-treatment reduces NADPH oxidase activity (<b>A</b>) and superoxide production (<b>B<...
<p>(<b>A</b>) NSC23766 significantly attenuated cerebral ischemia-induced Rac1 activity at 3 h after...
Recent work by our laboratory and others has implicated NADPH oxidase as having an important role in...
<p>(<b>A</b>) Representative staining of coronal CA1 sections with NeuN (red) show neuroprotection o...
Neural damage caused by ischemia/stroke is initiated by excess reactive oxygen species (ROS). Differ...
<p>(A) Cortical and hippocampal sections of cases with no cognitive impairment (NCI) and AD were dou...
The Ras-related C3 botulinum toxin substrate 1 (Rac1) belongs to the family of Ras-homologous small ...
<p>Immunofluorescent staining of 4-HNE in brain cortex (<b>A1</b>) and hippocampus CA1 region (<b>B1...
Growing evidence indicates that overproduction of reactive oxygen species (ROS) plays a prominent ro...
Growing evidence indicates that overproduction of reactive oxygen species (ROS) plays a prominent ro...
AbstractNeurons in the hippocampal CA1 region are particularly sensitive to oxidative stress (OS), w...
<p>(a) Oxidized 8-deoxyguanosine (8OHDG), a marker of oxidized nucleic acid and (c) hydroxynonenal (...
<p>8-OHDG levels in cortex and hippocampus of <i>gp91phox</i><sup>_<i>/Y</i></sup> and C57BL6/J mice...
The aim of this study was to clarify the relationship among Rac1 expression and activation, oxidativ...
PurposeThe active form of small GTPase RAC1 is required for activation of NADPH oxidase (NOX), which...
<p>NSC23766 pre-treatment reduces NADPH oxidase activity (<b>A</b>) and superoxide production (<b>B<...
<p>(<b>A</b>) NSC23766 significantly attenuated cerebral ischemia-induced Rac1 activity at 3 h after...
Recent work by our laboratory and others has implicated NADPH oxidase as having an important role in...
<p>(<b>A</b>) Representative staining of coronal CA1 sections with NeuN (red) show neuroprotection o...
Neural damage caused by ischemia/stroke is initiated by excess reactive oxygen species (ROS). Differ...
<p>(A) Cortical and hippocampal sections of cases with no cognitive impairment (NCI) and AD were dou...
The Ras-related C3 botulinum toxin substrate 1 (Rac1) belongs to the family of Ras-homologous small ...
<p>Immunofluorescent staining of 4-HNE in brain cortex (<b>A1</b>) and hippocampus CA1 region (<b>B1...
Growing evidence indicates that overproduction of reactive oxygen species (ROS) plays a prominent ro...
Growing evidence indicates that overproduction of reactive oxygen species (ROS) plays a prominent ro...
AbstractNeurons in the hippocampal CA1 region are particularly sensitive to oxidative stress (OS), w...
<p>(a) Oxidized 8-deoxyguanosine (8OHDG), a marker of oxidized nucleic acid and (c) hydroxynonenal (...
<p>8-OHDG levels in cortex and hippocampus of <i>gp91phox</i><sup>_<i>/Y</i></sup> and C57BL6/J mice...
The aim of this study was to clarify the relationship among Rac1 expression and activation, oxidativ...
PurposeThe active form of small GTPase RAC1 is required for activation of NADPH oxidase (NOX), which...