<p>WT (black bars) and OPN KO (white bars) mice were infected intranasally with 10<sup>3</sup> CFU of <i>B. pseudomallei</i> and bacterial loads were determined 24 and 72 h after infection in (A) lung, (B) blood, and (C) spleen. Data are expressed as means ± SEM; n = 8 mice/group, ** <i>P</i><0.01 as compared to WT mice. N.D. means not detectable.</p
<p>Mice were treated with non-immune IgG control (white bars) or anti-MIF antibodies (grey bars) and...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>Values represent the mean and standard deviation of cytokines and chemokines concentrations (pg/1...
<p>WT and MyD88 KO mice were intranasally infected with <i>B. pseudomallei</i> (5×10<sup>2</sup> CFU...
<p>Representative lung pathology of WT (A, D) and OPN KO (B, E) mice 24 (A–C) and 72 (D–F) h after i...
<p>(A) Percent survival of BALB/c mice (n = 8) infected via the intranasal route with the listed num...
<p>(A) The bacterial load in the lungs of mice was measured at 24 hr after i.n. infection with 100 L...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>BALB/c mice (n = 8–10 animals per time point) were inoculated orally with 5×10<sup>5</sup> CFU Bp...
<p>Proinflammatory cytokine (IL-12p70, IFN-<b>γ</b>, TNF-α and IL-6), anti-inflammatory IL-10 and ch...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>CD1 mice were inoculated intratracheal through oral lavage using feeding needle with 1.2×10<sup>6...
Wild-type mice were given broad-spectrum antibiotics or autoclaved saline. Three days after cessatio...
<p>WT (solid whiskers) and <i>st2</i><sup>−/−</sup> mice (open whiskers) were infected with 1.5×10<s...
<p>Lung pathology was determined in wild-type (WT; black bars) and <i>Trem-2</i><sup><i>-/-</i></sup...
<p>Mice were treated with non-immune IgG control (white bars) or anti-MIF antibodies (grey bars) and...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>Values represent the mean and standard deviation of cytokines and chemokines concentrations (pg/1...
<p>WT and MyD88 KO mice were intranasally infected with <i>B. pseudomallei</i> (5×10<sup>2</sup> CFU...
<p>Representative lung pathology of WT (A, D) and OPN KO (B, E) mice 24 (A–C) and 72 (D–F) h after i...
<p>(A) Percent survival of BALB/c mice (n = 8) infected via the intranasal route with the listed num...
<p>(A) The bacterial load in the lungs of mice was measured at 24 hr after i.n. infection with 100 L...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>BALB/c mice (n = 8–10 animals per time point) were inoculated orally with 5×10<sup>5</sup> CFU Bp...
<p>Proinflammatory cytokine (IL-12p70, IFN-<b>γ</b>, TNF-α and IL-6), anti-inflammatory IL-10 and ch...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>CD1 mice were inoculated intratracheal through oral lavage using feeding needle with 1.2×10<sup>6...
Wild-type mice were given broad-spectrum antibiotics or autoclaved saline. Three days after cessatio...
<p>WT (solid whiskers) and <i>st2</i><sup>−/−</sup> mice (open whiskers) were infected with 1.5×10<s...
<p>Lung pathology was determined in wild-type (WT; black bars) and <i>Trem-2</i><sup><i>-/-</i></sup...
<p>Mice were treated with non-immune IgG control (white bars) or anti-MIF antibodies (grey bars) and...
<p>Mice were inoculated intranasally with 750<i>B. pseudomallei</i> and sacrificed after 24, 48 and ...
<p>Values represent the mean and standard deviation of cytokines and chemokines concentrations (pg/1...