Phenotypic appearance of mouse PPCD1.

<p>Enucleated eyes were fixed in 10% formalin in phosphate-buffered saline and photographed. A. Appearance of PPCD1 mouse, showing the enlarged anterior chamber. B. Comparison of normal (left) and affected (right) eyes. Corneal neovascularization can be observed on the surface of the affected cornea. The arrow indicates an anterior synechia. Age, 3 months. C. Affected eye, showing corneal haze and cell growth across the surface of the pupil (arrow). Age, 3 months. D. Affected eye, showing lens subluxation, corneal haze, exudate in the anterior chamber, and anterior synechia. Age, 5 months.