<p>Comparison of exon models from vdB (red), vdB* (yellow), and intermediate (orange) genomes. All SNPs in the region are shown, with the SNP that perfectly correlates with the event in bold. A) A “shift” event. A SNP in a <i>TGA</i> stop codon in vdB* is associated with a shift in exon length on contig 16: 3577500–3576100. B) Two “shift” events. A novel splice donor in vdB* affects the length of its exon and a neighboring exon on contig 20: 2945150–2945750. C) An “intron gain/loss” event. An intronic SNP affects the presence/absence of an intron on contig 12: 69800–70950.</p
Deep sequencing has shown that over 90% of human genes undergo alternative splicing. The splicing pr...
With the availability of a large amount of genomic data it is expected that the influence of single ...
With the availability of a large amount of genomic data it is expected that the influence of single ...
<p>A–C) Diverse gene model phenotypes associated with a single SNP. A) A SNP is part of a start codo...
<p>Note that as each event can belong to one or more category (Intron gain/loss, Exon gain/loss, and...
<p>A) Gene model differences between vdB and vdB*, where all base pair changes were made at naturall...
Background Cryptic exons are typically characterised as deleterious splicing aberrations caused b...
<p>(A) The distribution of the number of predicted exon-skipping ISE SNPs observed for each of the 1...
<p>The main resource for identifying alternatively spliced exons was compiled using two data sources...
<p>(A) The list of high LD SNPs (r<sup>2</sup>≥0.5) in exons. The risk region number was derived fro...
Alternative splicing of genes is an efficient means of generating variation in protein function. Sev...
<p>A) Histogram of the correlation between every pair-wise event-SNP combination. A correlation of 1...
<p>Genomic regions were ranked according to their contribution in predicting gene expression. First,...
Alternative splicing of genes is an efficient means of generating variation in protein function. Sev...
With the availability of a large amount of genomic data it is expected that the influence of single ...
Deep sequencing has shown that over 90% of human genes undergo alternative splicing. The splicing pr...
With the availability of a large amount of genomic data it is expected that the influence of single ...
With the availability of a large amount of genomic data it is expected that the influence of single ...
<p>A–C) Diverse gene model phenotypes associated with a single SNP. A) A SNP is part of a start codo...
<p>Note that as each event can belong to one or more category (Intron gain/loss, Exon gain/loss, and...
<p>A) Gene model differences between vdB and vdB*, where all base pair changes were made at naturall...
Background Cryptic exons are typically characterised as deleterious splicing aberrations caused b...
<p>(A) The distribution of the number of predicted exon-skipping ISE SNPs observed for each of the 1...
<p>The main resource for identifying alternatively spliced exons was compiled using two data sources...
<p>(A) The list of high LD SNPs (r<sup>2</sup>≥0.5) in exons. The risk region number was derived fro...
Alternative splicing of genes is an efficient means of generating variation in protein function. Sev...
<p>A) Histogram of the correlation between every pair-wise event-SNP combination. A correlation of 1...
<p>Genomic regions were ranked according to their contribution in predicting gene expression. First,...
Alternative splicing of genes is an efficient means of generating variation in protein function. Sev...
With the availability of a large amount of genomic data it is expected that the influence of single ...
Deep sequencing has shown that over 90% of human genes undergo alternative splicing. The splicing pr...
With the availability of a large amount of genomic data it is expected that the influence of single ...
With the availability of a large amount of genomic data it is expected that the influence of single ...