Schematic diagram showing α-TEA to induce breast cancer cells to undergo apoptosis via caspase-8 mediated ER stress JNK/CHOP/DR5 amplification loop and by down-regulation of anti-apoptotic mediators c-FLIP (L) and Bcl-2.

<p>Schematic diagram showing α-TEA to induce breast cancer cells to undergo apoptosis via caspase-8 mediated ER stress JNK/CHOP/DR5 amplification loop and by down-regulation of anti-apoptotic mediators c-FLIP (L) and Bcl-2.