<p>The assays were performed in TZM-bl cells using virus stocks grown in RM PBMC. (A) Dotted lines, neutralization of SHIV-1157ipEL-p (circles), SHIV-1157ipEL-pΔ3N (red color with triangles) and SHIV-1157ipd3N4 (squares) using sCD4; solid lines, neutralization of the above SHIVs using the human nmAb b12. (B) Values represent the concentration (µg/ml) for sCD4 and human b12 at which relative luciferase units (RLU) were reduced 50% or 90% compared to virus control wells, respectively.</p
<p>TZMbl cells were infected with 200TCID<sub>50</sub> of 293T cell generated viral supernatant usin...
<p>SIV mAbs cloned from targeted B cell sorts to isolate CD4bs-, CVNbs-and V1V2-specific B cells. In...
<p>(A-B) Several cell lines were compared for use in the luciferase assay. The x-axis indicates hour...
<p>The selection of SHIV<sub>SF162P3</sub> for the protection study was based on the results of 2G12...
<p>Low doses of the relatively neutralization resistant SHIV <sub>SF162P3</sub> isolate were incubat...
<p>Spectrum of neutralization sensitivity of R5 SHIV strains encoding HIV clade B or C <i>env</i>. S...
<p>Low doses of the relatively neutralization sensitive SHIV <sub>SF162P4</sub> isolate were incubat...
#<p>Numbers given are the sample dilutions at which relative luminescence units (RLU) were reduced b...
<p>Inhibition of infection using HIV-1+ sera and multiple viral forms (pseudovirus, biological isola...
<p>Neutralization assays were performed in M7-Luc cells (for SHIVs) or TZM-bl cells (for HIVs) <a hr...
<p><b>A</b>-<b>C</b>. <b>Neutralization sensitivity of three tier 2 subtype B IMC.LucR transmitted/f...
<p>Infectivity of the virus treated with a ligand was assessed in TZM-bl cells at different time poi...
<p>HEK 293T cells supernatant of newly generated stHIV with Env375H or Env 375Y viruses were infecte...
<p>IC50 values are color coded as indicated. Control bnAb produced in CHO (C) and VRC01 produced in ...
Circos plot showing binding or neutralization of B cell supernatants as determined by ELISA and neut...
<p>TZMbl cells were infected with 200TCID<sub>50</sub> of 293T cell generated viral supernatant usin...
<p>SIV mAbs cloned from targeted B cell sorts to isolate CD4bs-, CVNbs-and V1V2-specific B cells. In...
<p>(A-B) Several cell lines were compared for use in the luciferase assay. The x-axis indicates hour...
<p>The selection of SHIV<sub>SF162P3</sub> for the protection study was based on the results of 2G12...
<p>Low doses of the relatively neutralization resistant SHIV <sub>SF162P3</sub> isolate were incubat...
<p>Spectrum of neutralization sensitivity of R5 SHIV strains encoding HIV clade B or C <i>env</i>. S...
<p>Low doses of the relatively neutralization sensitive SHIV <sub>SF162P4</sub> isolate were incubat...
#<p>Numbers given are the sample dilutions at which relative luminescence units (RLU) were reduced b...
<p>Inhibition of infection using HIV-1+ sera and multiple viral forms (pseudovirus, biological isola...
<p>Neutralization assays were performed in M7-Luc cells (for SHIVs) or TZM-bl cells (for HIVs) <a hr...
<p><b>A</b>-<b>C</b>. <b>Neutralization sensitivity of three tier 2 subtype B IMC.LucR transmitted/f...
<p>Infectivity of the virus treated with a ligand was assessed in TZM-bl cells at different time poi...
<p>HEK 293T cells supernatant of newly generated stHIV with Env375H or Env 375Y viruses were infecte...
<p>IC50 values are color coded as indicated. Control bnAb produced in CHO (C) and VRC01 produced in ...
Circos plot showing binding or neutralization of B cell supernatants as determined by ELISA and neut...
<p>TZMbl cells were infected with 200TCID<sub>50</sub> of 293T cell generated viral supernatant usin...
<p>SIV mAbs cloned from targeted B cell sorts to isolate CD4bs-, CVNbs-and V1V2-specific B cells. In...
<p>(A-B) Several cell lines were compared for use in the luciferase assay. The x-axis indicates hour...