Induction of lethality in mice by intestinal <i>E. coli</i>-derived OMVs.

<p>Mice were administered intraperitoneally once with 200 µl PBS that contained 0, 15, 25, or 50 µg OMVs derived from <i>E. coli</i>. Survival was monitored every 12 h for 5 days (<i>n</i> = 20; ***<i>P</i><0.001, compared to the PBS group).