Labile Zn pools are not associated with lysosomes.

<p>Representative confocal micrographs of lysosomes detected with Lysotracker Green in untreated cells (Lysotracker) and cells treated with chloroquine diphosphate (Lysotracker +CLQ).. Images verify that chloroquine diphosphate disrupts lysosomes in HC11 cells. Representative confocal micrographs of “labile” Zn pools detected using FluoZin-3 in untreated cells (FluoZin-3) and cells treated with chloroquine diphosphate (FluoZin-3 +CLQ). Images illustrate that the distribution of “labile” Zn pools in mammary cells is not affected by lysosomal disruption.