<p>(A) Domain structure of Cux1 protein. Constructed deletions of Cux1 are indicated. (B) Representative cells after transfection of different deletions of Cux1. Scale bars: 50 µm. (C–D) Quantification of the dendritic complexity for cells transfected with various Cux1 deletions. Data shown are mean ± SEM (n≥30 for each condition). ** <i>P</i><0.01, ANOVA SNK test. (E) Localization of Cux1 deletions in cortical pyramidal neurons in culture. Cux1 and Cux1-deletions were tagged with GFP to reveal their subcellular localization. Propidium iodide (PI) was used to indicate the nuclei. DIC: differential interference contrast. Scale bar: 50 µm.</p
<p>(A) Typical morphology of the pyramidal and granule cell at DIV 4. Cells were isolated from P0 hi...
<p>(A) Average number of the terminal dendritic ends in wild type, <i>cul1</i> and <i>cul3</i> mutan...
Cullin-9 (CUL9) is a member of the Cullin ubiquitin ligase family strongly expressed in the brain. R...
<p>(A) Representative examples of transfected neurons at DIV6. Scale bars: 50 µm. (B–C) The dendriti...
In the murine cerebral cortex, mammalian homologues of the Cux family transcription factors, Cux1 an...
<p>(A–B) RT-PCR analysis of Cux expression level following RNAi treatments. Two specific RNAi each d...
<p>(A) RT-PCR analysis of p27 and NCAM expression levels after overexpression of Cux proteins. Repre...
<p>(A–B) Both p27<sup>ck-</sup> (p27 deficient in the interaction with cyclins and Cdks) and p27-CT ...
© 2014 Wiley Periodicals, Inc. A number of recent reports implicate the differential regulation of a...
SummaryDendrite branching and spine formation determines the function of morphologically distinct an...
<p>(A–B) Increase of p27 expression level by transfection of Cux1-RNAi plasmids into cultured cortic...
Projection neurons destined for the cortical plate are generated sequentially from the proliferative...
<p>(A) Typical morphology of pyramidal cells, granule cells and interneurons. The cell type was char...
<p><b>Dendritic complexity was</b> measured as number of intersections per shell as a function of di...
Sholl analysis (A) and dendritic length measurements (B) to assess dendritic complexity of ZBTB20-ex...
<p>(A) Typical morphology of the pyramidal and granule cell at DIV 4. Cells were isolated from P0 hi...
<p>(A) Average number of the terminal dendritic ends in wild type, <i>cul1</i> and <i>cul3</i> mutan...
Cullin-9 (CUL9) is a member of the Cullin ubiquitin ligase family strongly expressed in the brain. R...
<p>(A) Representative examples of transfected neurons at DIV6. Scale bars: 50 µm. (B–C) The dendriti...
In the murine cerebral cortex, mammalian homologues of the Cux family transcription factors, Cux1 an...
<p>(A–B) RT-PCR analysis of Cux expression level following RNAi treatments. Two specific RNAi each d...
<p>(A) RT-PCR analysis of p27 and NCAM expression levels after overexpression of Cux proteins. Repre...
<p>(A–B) Both p27<sup>ck-</sup> (p27 deficient in the interaction with cyclins and Cdks) and p27-CT ...
© 2014 Wiley Periodicals, Inc. A number of recent reports implicate the differential regulation of a...
SummaryDendrite branching and spine formation determines the function of morphologically distinct an...
<p>(A–B) Increase of p27 expression level by transfection of Cux1-RNAi plasmids into cultured cortic...
Projection neurons destined for the cortical plate are generated sequentially from the proliferative...
<p>(A) Typical morphology of pyramidal cells, granule cells and interneurons. The cell type was char...
<p><b>Dendritic complexity was</b> measured as number of intersections per shell as a function of di...
Sholl analysis (A) and dendritic length measurements (B) to assess dendritic complexity of ZBTB20-ex...
<p>(A) Typical morphology of the pyramidal and granule cell at DIV 4. Cells were isolated from P0 hi...
<p>(A) Average number of the terminal dendritic ends in wild type, <i>cul1</i> and <i>cul3</i> mutan...
Cullin-9 (CUL9) is a member of the Cullin ubiquitin ligase family strongly expressed in the brain. R...