<p>NAA/Cr over the course of SIV infection in untreated animals (solid squares), minocycline (MN)-treated persistently CD8-depleted animals (open circles) and MN-treated short-term CD8-depleted animals (solid triangles). Mean NAA/Cr measured in the parietal cortex (<b>A</b>), frontal cortex (<b>B</b>), basal ganglia (<b>C</b>) and white matter semiovale (<b>D</b>) are plotted over time. Error bars represent standard error of the mean. The arrows represent the time point when minocycline (MN) treatment was initiated.</p
<p>The release of TNF-α (<b>A</b>) and the percentage of proliferating microglial cells (determined ...
Hallenged with either saline or LPS i.p and A) IL-1β, B) IL-6, and C) IDO mRNA levels were determine...
<p>(A) The number of AV in neurites decreased significantly in neurons exposed to the SIV-infected m...
<p>Mean viral load in untreated animals (solid squares), minocycline (MN)-treated persistently CD8-d...
<p>(<b>A</b>) NAA/Cr at the last MR scan is significantly different among the three cohorts in all f...
<p>(A) A decreased NAA/Cr ratio in frontal cortex (FC), (B) parietal cortex (PC), (C) basal ganglia ...
<p>(<b>A</b>) IBA-1 expression in four representative sections from each of an uninfected, CD8-deple...
<p>A. The decrease in NAA/Cr was arrested with this regimen of combination antiretroviral treatment ...
<p>Regression analyses were performed between the absolute numbers of each monocyte subset and the p...
<p>The minocycline attenuated hypersensitivity to innocuous mechanical stimulation of the left hind-...
<p>Comparison of cultures incubated from DIV 1 or DIV 4 onwards and analyzed at DIV 7. (<b>A</b>) Nu...
<p>A. Treated animals revealed lower plasma vRNA levels (~1 log) at endpoints when compared to untre...
<p>Comparison of organotypic spinal cord cultures incubated with minocycline starting at DIV 1 or DI...
Minocycline is a tetracycline antibiotic that has been proposed as a potential conjunctive therapy f...
<p><i>A</i>, Expression of RGMa (green) by CD11b-positive microglia (red) in the lesion epicenter at...
<p>The release of TNF-α (<b>A</b>) and the percentage of proliferating microglial cells (determined ...
Hallenged with either saline or LPS i.p and A) IL-1β, B) IL-6, and C) IDO mRNA levels were determine...
<p>(A) The number of AV in neurites decreased significantly in neurons exposed to the SIV-infected m...
<p>Mean viral load in untreated animals (solid squares), minocycline (MN)-treated persistently CD8-d...
<p>(<b>A</b>) NAA/Cr at the last MR scan is significantly different among the three cohorts in all f...
<p>(A) A decreased NAA/Cr ratio in frontal cortex (FC), (B) parietal cortex (PC), (C) basal ganglia ...
<p>(<b>A</b>) IBA-1 expression in four representative sections from each of an uninfected, CD8-deple...
<p>A. The decrease in NAA/Cr was arrested with this regimen of combination antiretroviral treatment ...
<p>Regression analyses were performed between the absolute numbers of each monocyte subset and the p...
<p>The minocycline attenuated hypersensitivity to innocuous mechanical stimulation of the left hind-...
<p>Comparison of cultures incubated from DIV 1 or DIV 4 onwards and analyzed at DIV 7. (<b>A</b>) Nu...
<p>A. Treated animals revealed lower plasma vRNA levels (~1 log) at endpoints when compared to untre...
<p>Comparison of organotypic spinal cord cultures incubated with minocycline starting at DIV 1 or DI...
Minocycline is a tetracycline antibiotic that has been proposed as a potential conjunctive therapy f...
<p><i>A</i>, Expression of RGMa (green) by CD11b-positive microglia (red) in the lesion epicenter at...
<p>The release of TNF-α (<b>A</b>) and the percentage of proliferating microglial cells (determined ...
Hallenged with either saline or LPS i.p and A) IL-1β, B) IL-6, and C) IDO mRNA levels were determine...
<p>(A) The number of AV in neurites decreased significantly in neurons exposed to the SIV-infected m...