Similarity overlap and recognition rates (%) of designed and random sequences.

<p><i>^a</i>Using the general PSSMs (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0010410#s2" target="_blank">Methods</a>).</p><p><i>^b</i>Using the backbone-specific PSSMs.</p><p><i>^c</i>Overlap with the similarity scores for the small (top line) and large (bottom line) Pfam ensembles of natural sequences.