Effect of LJK-11 on tubulin polymerization.

<p>Effects of LJK-11 (250 µM), colchicines (10 µM), nocodazole (10 µM), or Taxol (10 µM) on bovine brain tubulin polymerization were measured turbidimetrically(A). Effects of 1 µM, 5 µM, 25 µM, 100 µM, 200 µM LJK-11 on bovine brain tubulin polymerization were also measured. Changes in absorbance at 340 nm (A₃₄₀) were measured and plotted as a function of time(B).