Age-dependent upregulation of CpG-induced production of IP-10 and MIG.

<p>Whole blood samples were stimulated with CpG A+B combination and culture supernatants were collected after 16–18 h. Production in the different infant groups was compared to adult values. Cord blood (CB, n = 13), 3-month (3 m, n = 10), 6&9-month (6 m, n = 3, 9 m, n = 5), 12-month (12 m, n = 11) old infants and healthy adults (n = 10). Data are represented as median+interquartile range. *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001 as compared to stimulated adult samples.