<p>B cell (panel a) and CD4 T cell (panel b) population during a typical immunization experiment. An immunogenic molecule is injected at time zero and after six months. In both plots, the total number of lymphocytes along with the immune memory compartment are shown. Panel (c) shows that the secondary response eliminates the antigen on a shorter timescale due to the presence of memory cells ready to react.</p
Accurate immunological models offer the possibility of performing high- throughput experiments in si...
This work describes a computer model of the immune system s response to infection, specifically the ...
<p>In each 10 day simulation run, with a starting population of 100 k T cells, the external inflamma...
Computational methods have been developped to simulate the complex interactions between components o...
<p>Panel (a) shows the distribution of the time to clear the antigen in five hundred simulations wit...
Immunological memory is a cardinal feature of the adaptive immune response and the generation of lon...
Motivation: Although results from phase III clinical trials substantially support the use of prophyl...
<p>Vaccination protocols are defined by initially setting a total antigen dose. A percentage of this...
Abstract only availableThe function of memory T cells is the primary factor in vaccine efficacy. In ...
<div><p>(A,B) Effect of proportion of infected cells becoming latently infected quiescent memory T l...
<p>Top: (a) Time evolution of the population dynamics of LCMV specific memory CD8+ T cells following...
Each row represents the peak CD4+ T cell response in a Monte Carlo simulation, where 50 realizations...
This paper examines the numerical and functional consequences of various stimuli on antiviral CD8+ T...
Triggering an appropriate protective response against invading agents is crucial to the effectivenes...
The battleground of infectious disease enlists two chief forces: the defending immune system, and th...
Accurate immunological models offer the possibility of performing high- throughput experiments in si...
This work describes a computer model of the immune system s response to infection, specifically the ...
<p>In each 10 day simulation run, with a starting population of 100 k T cells, the external inflamma...
Computational methods have been developped to simulate the complex interactions between components o...
<p>Panel (a) shows the distribution of the time to clear the antigen in five hundred simulations wit...
Immunological memory is a cardinal feature of the adaptive immune response and the generation of lon...
Motivation: Although results from phase III clinical trials substantially support the use of prophyl...
<p>Vaccination protocols are defined by initially setting a total antigen dose. A percentage of this...
Abstract only availableThe function of memory T cells is the primary factor in vaccine efficacy. In ...
<div><p>(A,B) Effect of proportion of infected cells becoming latently infected quiescent memory T l...
<p>Top: (a) Time evolution of the population dynamics of LCMV specific memory CD8+ T cells following...
Each row represents the peak CD4+ T cell response in a Monte Carlo simulation, where 50 realizations...
This paper examines the numerical and functional consequences of various stimuli on antiviral CD8+ T...
Triggering an appropriate protective response against invading agents is crucial to the effectivenes...
The battleground of infectious disease enlists two chief forces: the defending immune system, and th...
Accurate immunological models offer the possibility of performing high- throughput experiments in si...
This work describes a computer model of the immune system s response to infection, specifically the ...
<p>In each 10 day simulation run, with a starting population of 100 k T cells, the external inflamma...