mDC from <i>S. haematobium</i>-infected subjects have an altered MAPK signaling, but not TLR4 expression profile.

<p>(A) TLR4 expression was analysed on mDC present in PBMC following the gating strategy as described in legend of <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000667#pntd-0000667-g001" target="_blank">Fig. 1</a>. (B and C) 20 and 60 minutes after stimulation with LPS, mDC were intracellularly stained for (B) phospophorylated p38 and ERK and (C) the ratio between <i>p</i>-ERK and <i>p</i>-p38 was determined by dividing the respective mean fluorescence intensities per sample. Each group represents data from 5 donors. (A) Bars represent mean + SD. (B and C) box plots represent 25–75 percentile range with error bars showing minimum to maximum.