Canine pyometra

Pyometra - it is a life-threatening illness, for this reason, it is necessary to quickly and accurately determine the disease. The aim of the study was to evaluate influence of breed and season on pyometra manifestation. The time period was determined between the end of the heat and the first clinical signs of the disease. To evaluate the parameters of blood morphology and biochemistry, their clinical significance in pyometra diagnostics. Three groups of different sizes and breeds were studied. The first group consisted of 10 large breed bitches. The second group consisted of 6 medium-sized breed bitches. The third group consisted of 4 small breed bitches. One factor connected all of them – they all had pyometra. 12 different breeds of bitches were studied, they were all assigned to 3 different size and breed groups. The influence of such breed frequency fluctuations is genetic predisposition The pyometra occurred during the summer and autumn seasons. For the 60 % of the first group of bitches, the pyometra occured in autumn. 83.3 % of the second group and 75 % of the third group bitches, the pyometra occured in the summer. The longest time period from the end of the heat to the first clinical signs manifestation was found in the medium breeds – 55,83 ± 5,7 days. The shortest average time was found in small breeds - 53,5 ± 28,26 days. Analyzing the results of blood morphological and biochemical studies, it is possible to evaluate systemic changes in the body. Leukocytosis and neutrophilia was determined in 60 % of large breed bitches, 83,3 % in medium size group and 100 % in the first group of small breed bitches. The average number of leukocytes was calculated: first group of bitches - 27,2 ± 19,2 × 109/L, second group - 32,6 ± 26,1 × 109/L, third group - 34,2 ± 16,7 × 109/L. The average number of neutrophils was determined: first group of bitches - 21,8 ± 15,5 × 109/L; second group - 31,3 ± 19,8 × 109/L, third group - 27 ± 16,5 × 109/L. The studied bitches did not experience any kidney and liver function problems. Creatinine and glutamate pyruvate transaminase concentration in the blood of bitches did not exceed the limits of the physiological norm