Background: Ulcerative Colitis (UC) is an aggressive and incurable inflammatory bowel disease that affects young people typically in their teens and early twenties. The symptoms of UC include, bloody diarrhoea, incontinence and intractable fatigue that can be difficult to treat. There are almost 250, 000 patients with UC in the UK alone. Patients with UC for more than 8 years have a ten times increased risk of bowel cancer and undergo regular endoscopic surveillance of their large bowel. Unfortunately almost 50% of cancers are missed even in patients on surveillance. Furthermore cancer can develop in between surveillance episodes. There is a clear need to develop improved ways of predicting cancer in such patients. Pilot data: DNA methyl...
BACKGROUND: Patients with ulcerative colitis are at a higher risk of developing colorectal cancer th...
Inflammation can result from a range of sources including microbial infections, exposure to allergen...
Ulcerative colitis (UC) is an inflammatory bowel disease, associated with increased lifetime risk of...
BackgroundChronic ulcerative colitis is a large bowel inflammatory condition associated with increas...
Background: Patients with ulcerative colitis and Crohn's colonic disease are at increased risk of de...
Background: The risk of developing colorectal cancer (CRC) is increased in patients with inflammator...
Ulcerative colitis (UC) is an inflammatory condition affecting the mucosa of the large bowel and the...
Background- Colorectal cancer (CRC) is the third most common epithelial carcinoma. There is an incre...
BACKGROUND:Chronic inflammation caused by ulcerative colitis (UC) causes a pro-neoplastic drive in t...
Background: Although DNA methylation of colonic mucosa in ulcerative colitis (UC) has been suggested...
Background: Chronic inflammation caused by ulcerative colitis (UC) causes a pro-neoplastic drive in ...
textabstractRegular colonoscopic surveillance for detection of dysplasia is recommended in longstand...
The association between ulcerative colitis (UC) and cancer in a defined geographical region in Swede...
Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal...
Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal...
BACKGROUND: Patients with ulcerative colitis are at a higher risk of developing colorectal cancer th...
Inflammation can result from a range of sources including microbial infections, exposure to allergen...
Ulcerative colitis (UC) is an inflammatory bowel disease, associated with increased lifetime risk of...
BackgroundChronic ulcerative colitis is a large bowel inflammatory condition associated with increas...
Background: Patients with ulcerative colitis and Crohn's colonic disease are at increased risk of de...
Background: The risk of developing colorectal cancer (CRC) is increased in patients with inflammator...
Ulcerative colitis (UC) is an inflammatory condition affecting the mucosa of the large bowel and the...
Background- Colorectal cancer (CRC) is the third most common epithelial carcinoma. There is an incre...
BACKGROUND:Chronic inflammation caused by ulcerative colitis (UC) causes a pro-neoplastic drive in t...
Background: Although DNA methylation of colonic mucosa in ulcerative colitis (UC) has been suggested...
Background: Chronic inflammation caused by ulcerative colitis (UC) causes a pro-neoplastic drive in ...
textabstractRegular colonoscopic surveillance for detection of dysplasia is recommended in longstand...
The association between ulcerative colitis (UC) and cancer in a defined geographical region in Swede...
Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal...
Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential colorectal...
BACKGROUND: Patients with ulcerative colitis are at a higher risk of developing colorectal cancer th...
Inflammation can result from a range of sources including microbial infections, exposure to allergen...
Ulcerative colitis (UC) is an inflammatory bowel disease, associated with increased lifetime risk of...