Effect of doxycycline on MMP-2 in the infarct border zone six weeks after MI.
- Kimberly Spaulding (797016)
- Kiyoaki Takaba (4846765)
- Alexander Collins (4846762)
- Farshid Faraji (4846756)
- Guanying Wang (758781)
- Esteban Aguayo (4846753)
- Liang Ge (541067)
- David Saloner (525523)
- Arthur W. Wallace (4846759)
- Anthony J. Baker (433896)
- David H. Lovett (173834)
- Mark B. Ratcliffe (4479631)
Publication date
February 2018
DOIAbstract
<p>Panel <b>A</b> shows the effect on MMP-2 using immunohistochemistry and panels <b>B</b> and <b>C</b> show western blot results. Panel <b>A</b> subpanels <b>C</b> and <b>D</b> were done using Nomarski optics. FL-MMP-2 staining is sarcomeric while the NTT-MMP-2 staining shows punctate, linear arrays of antibody staining between sarcomeres (black arrows). *p< 0.05. The effect of doxycycline on full length (<b>D</b>) and truncated (<b>E</b>) MMP-2 RNA. *p<0.05 for combined FL-MMP-2 and NTT-MMP-2 RNA effect. n = 4 for MI control and MI + Dox groups, n = 2 for non-operated control.</p
Add to ORKG