Bias as a function of <i>K</i>_<i>i</i>.

<p>The simulated results are represented by the solid symbols connected with lines. In these cases, the x-axis represents the simulated <i>K</i>_<i>i</i> value while the y-axis is the mean <i>K</i>_<i>i</i> of the simulation minus the simulated value. Symbols along the line are simulations with the same <i>K</i>_<i>1</i> and <i>V</i>_<i>ND</i> but a different <i>k</i>_<i>3</i>. <i>K</i>₁ = 0.16 mL·cm^-3·min^-1 (Low rCBF), <i>K</i>₁ = 0.36 mL·cm^-3·min^-1 (high rCBF), <i>V</i>_<i>ND</i> = 2, 4 and 4.5 mL·cm^-3(Low, High, very high respectively). Scattered points are data from real images (6 subjects/9 ROIs/2 scans per subject). In these cases, <i>K</i>_<i>i</i> in the x-axis is the result of the 2TCMi on the regional TAC while the y-axis is the regional mean of <i>K</i>_<i>i</i> in the BAFPIC based parametric map minus the regional 2TCMi estimation. BAFPIC was applied with 50 function with θ in the range [0.06 3] min^-1 and <i>V</i>_<i>B</i> = 5%.