<p>Residues that were mutated from the native VRC23 sequence were compared to known antibodies. Proteins shown are VRC23 (PDB ID: 4j6r); VRC01 (3ngb); VRC-CH31 (4lsp); 3BNC117 (4jpv); and NIH45-46 (3u7y).</p
<p>Signature motifs recognized by each monoclonal antibody are shown in the second column: the numbe...
Glycoprotein B (gB, gpUL55) is the major antigen for the induction of neutralizing antibodies agains...
Little is known about the specificities and neutralization breadth of the H7-reactive antibody reper...
<p>For BROAD and MSD sequences a percentage similarity to the VRC01 lineage was computed (similarity...
<p>A. Predicted breadth of 10 redesigned antibodies generated either by BROAD or multistate design. ...
<p><b>(A)</b> Top (left panel) and side (right panel) views of the crystal structure of the WNV E pr...
<p>a) H-S52 is close to the positive sidechain of K400 in DenV1. Mutating it to the negatively charg...
Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against ...
AbstractGlycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies ...
Monoclonal antibody 2909 belongs to a class of potently neutralizing antibodies that recognize quate...
<p><b>A</b>) Longitudinal neutralization of ConC V2 mutants. ConC wild-type (wt) is shown in red. V2...
Antibodies are key players of the immune system in higher vertebrates, which provide a defense again...
<p><b>A</b>. Left. CryoEM map of quaternary complex with antibody vFP1.01, segmented by components a...
<p>A. Amino acid residues in C2V3 region of the LT5.J4b Env that modulated neutralization sensitivit...
Three highly pathogenic β-coronaviruses have crossed the animal-to-human species barrier in the past...
<p>Signature motifs recognized by each monoclonal antibody are shown in the second column: the numbe...
Glycoprotein B (gB, gpUL55) is the major antigen for the induction of neutralizing antibodies agains...
Little is known about the specificities and neutralization breadth of the H7-reactive antibody reper...
<p>For BROAD and MSD sequences a percentage similarity to the VRC01 lineage was computed (similarity...
<p>A. Predicted breadth of 10 redesigned antibodies generated either by BROAD or multistate design. ...
<p><b>(A)</b> Top (left panel) and side (right panel) views of the crystal structure of the WNV E pr...
<p>a) H-S52 is close to the positive sidechain of K400 in DenV1. Mutating it to the negatively charg...
Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against ...
AbstractGlycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies ...
Monoclonal antibody 2909 belongs to a class of potently neutralizing antibodies that recognize quate...
<p><b>A</b>) Longitudinal neutralization of ConC V2 mutants. ConC wild-type (wt) is shown in red. V2...
Antibodies are key players of the immune system in higher vertebrates, which provide a defense again...
<p><b>A</b>. Left. CryoEM map of quaternary complex with antibody vFP1.01, segmented by components a...
<p>A. Amino acid residues in C2V3 region of the LT5.J4b Env that modulated neutralization sensitivit...
Three highly pathogenic β-coronaviruses have crossed the animal-to-human species barrier in the past...
<p>Signature motifs recognized by each monoclonal antibody are shown in the second column: the numbe...
Glycoprotein B (gB, gpUL55) is the major antigen for the induction of neutralizing antibodies agains...
Little is known about the specificities and neutralization breadth of the H7-reactive antibody reper...