<p>Analyses of (A) heart rate (HR), (B) systolic (SAP), (C) diastolic aortic pressure (DAP), (D) left ventricular systolic pressure (LVSP), (E) left ventricular end-diastolic pressure (LVEDP), rates of (F) contraction (+dp/dt) and (G) of relaxation (–dp/dt) were performed in anaesthetised WT or sAC KO mice 2 weeks after TAC or sham surgery. Data are expressed as means ± SEM, n = 9–12, ***(P< 0.001), *(P<0.05).</p
(A) The HW/BW ratio between male Sirt5 KO mice and WT littermates at 5 weeks after TAC surgery (n = ...
<p>LVP, left ventricle (LV) pressure; LVESP, LV end-systolic pressure; LVEDP, LV end-diastolic press...
<p>HR, heart rate; ESP, end-systolic pressure; EDP, end-diastolic pressure; ESV, end-systolic volume...
<p>(A) A<sub>2A</sub>-R mice had preserved cardiac function and showed tolerance to TAC-induced pres...
<p>3 d of pressure overload increased the left ventricular systolic pressure (A) and mean arterial b...
<p>WT – Wildtype; CYP – CYP2J2 overexpressing mice; TAC – Transverse aortic constriction; HR – Heart...
Cardiac hypertrophy was induced by TAC in male mice. Eight weeks following TAC, left ventricular car...
(A-F) Left ventricular cardiac functional parameters between male Sirt5 KO mice and WT littermates a...
<p>(A) Control (con) and transgenic (tg) mice of line B received Dox via food pellets throughout the...
<p>LVEF: Left ventricular ejection fraction; MAPSE: Mitral annular plane systolic excursion. E/E′: P...
<p>FS = fractional shortening;</p>*<p>P<0.05;</p>#<p>P<0.001 vs WT sham control.</p
<p>Both AGT KO mice and the C57BL/6 WT littermates were pretreated with or without Src kinase inhibi...
<p>Characteristics and echocardiography measurements from WT and FABP4-TG mice 2 weeks after TAC or ...
<p>WT, Wild type; PTX3-KO, PTX3 systemic knockout mice; TAC, thoracic aortic constriction; BW, body ...
<p>HR, heart rate; ESP, end-systolic pressure; EDP, end-diastolic pressure; ESV, end-systolic volume...
(A) The HW/BW ratio between male Sirt5 KO mice and WT littermates at 5 weeks after TAC surgery (n = ...
<p>LVP, left ventricle (LV) pressure; LVESP, LV end-systolic pressure; LVEDP, LV end-diastolic press...
<p>HR, heart rate; ESP, end-systolic pressure; EDP, end-diastolic pressure; ESV, end-systolic volume...
<p>(A) A<sub>2A</sub>-R mice had preserved cardiac function and showed tolerance to TAC-induced pres...
<p>3 d of pressure overload increased the left ventricular systolic pressure (A) and mean arterial b...
<p>WT – Wildtype; CYP – CYP2J2 overexpressing mice; TAC – Transverse aortic constriction; HR – Heart...
Cardiac hypertrophy was induced by TAC in male mice. Eight weeks following TAC, left ventricular car...
(A-F) Left ventricular cardiac functional parameters between male Sirt5 KO mice and WT littermates a...
<p>(A) Control (con) and transgenic (tg) mice of line B received Dox via food pellets throughout the...
<p>LVEF: Left ventricular ejection fraction; MAPSE: Mitral annular plane systolic excursion. E/E′: P...
<p>FS = fractional shortening;</p>*<p>P<0.05;</p>#<p>P<0.001 vs WT sham control.</p
<p>Both AGT KO mice and the C57BL/6 WT littermates were pretreated with or without Src kinase inhibi...
<p>Characteristics and echocardiography measurements from WT and FABP4-TG mice 2 weeks after TAC or ...
<p>WT, Wild type; PTX3-KO, PTX3 systemic knockout mice; TAC, thoracic aortic constriction; BW, body ...
<p>HR, heart rate; ESP, end-systolic pressure; EDP, end-diastolic pressure; ESV, end-systolic volume...
(A) The HW/BW ratio between male Sirt5 KO mice and WT littermates at 5 weeks after TAC surgery (n = ...
<p>LVP, left ventricle (LV) pressure; LVESP, LV end-systolic pressure; LVEDP, LV end-diastolic press...
<p>HR, heart rate; ESP, end-systolic pressure; EDP, end-diastolic pressure; ESV, end-systolic volume...