DNA photodamage in mice skin infected with MRSA and exposed to UVC light.

<p>A) Representative cross-sectional images of dorsal skin comparing the percentage of pre-mutagenic skin lesions CPD in keratinocytes (dark-stained cells) two or seven days after exposure to 40 or 300 mJ/cm² from the 222-nm or 254-nm light to that of skin incisions that were uninfected by applying saline prior to exposure to either UV lamp (Saline). Skin incisions that were infected but not exposed to the UV light (MRSA) represented the positive controls; B) Quantification of keratinocytes showing CPD; values represent the average ± SD measured in nine randomly selected field of view per mouse. *p< 0.05, **p< 0.005 compared to positive controls (MRSA).