Caspase activity in NCoR2 over-expressing HNO97, HNO124 and HNO210 cells.

<p>Cells were transfected with pCMV6-NCoR2 plasmid (or the empty vector pCMV6). Caspase activity was assessed at 24 h post-transfection in HNO97 <b>(a)</b>, HNO124 <b>(b)</b> and HNO210 <b>(c)</b> cells. Results were normalized to the corresponding activity in cells transfected with the pCMV6 empty vector, set to 1. *significantly different from pCMV6-transfected cells, p<0.05, n = 3. As a positive control, cells were treated with staurosporine (1 μM, 24 h), a known inductor of apoptosis. Subsequently, caspase activity was assessed in HNO97 <b>(d)</b>, HNO124 <b>(e)</b> and HNO210 <b>(f)</b> cells. Results were normalized to the corresponding measurements in control cells (vehicle treated), set to 1. Data are expressed as mean ± S.D. *significantly different from control cells, p<0.05, n = 3.