Longitudinal dynamics of biomarkers in Huntington’s disease including YKL-40, NFL, T-tau and P-tau.

<p>Longitudinal biomarker dynamics of (<b>A</b>) Neurofilament light levels (NFL), (<b>B</b>) YKL-40 and (<b>C</b>) Total Tau (T-tau), and (<b>D</b>) Phospho-tau (P-tau). Each line represents one individual, starting at the first CSF sample and protein concentration, finishing at the time of the second sample and concentration.