IPA of ethanol-treated macrophages reveals carbohydrate metabolism (A) and liver disease (B) as significant protein networks.

<p>The shapes represent the molecular classes of the proteins, as indicated in legend. The color is used to indicate the direction of regulation (red, upregulated; green, downregulated), while the color shade indicates the relative magnitude of change in protein intensities. The proteins functional interactions networks were generated through the use of IPA (QIAGEN Inc., <a href="https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/" target="_blank">https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/</a>) (37).