<p><b>A):</b> Airyscan micrographs of PPP with added thrombin to form extensive fibrin fibres from an individual with Parkinson’s disease (PD); <b>B)</b> PPP from the same individual, but exposed to 2ng.L<sup>-1</sup> LPS-binding protein followed by addition of thrombin. Thioflavin T (ThT) (5 μM) was added before thrombin. Micrographs were taken with a Zeiss LSM 510 META confocal microscope with a Plan-Apochromat 63x/1.4 Oil DIC objective. <b><i>LBP dramatically reduced the fluorescence seen in samples from patients with PD</i>.</b> Gain settings were kept the same during all data capturing and not changed for statistical analysis, but brightness and contrast was slightly adjusted for fig preparation.</p
Parkinson's disease (PD) is a well-known neurodegenerative disease with a strong association establi...
INTRODUCTION: Lipopolysaccharide (LPS) is the outer membrane component of Gram-negative bacteria. LP...
Parkinson’s disease (PD) is one of the most common neurodegenerative movement disorders which is cha...
<p><b>A and B)</b> Clot structure from two healthy individuals, imaged in an SEM and showing a ‘norm...
The thrombin-induced polymerisation of fibrinogen to form fibrin is well established as a late stag...
The thrombin-induced polymerisation of fibrinogen to form fibrin is well established as a late stage...
Dataset for paper. ALSO see link to raw figure data files stored at the following link:<div><br></d...
Many studies indicate that there is a (mainly dormant) microbial component in the progressive develo...
CITATION: Pretorius, E., Mbotwe, S. & Kell, D. B. 2017. Lipopolysaccharide-binding protein (LBP) rev...
CITATION: Pretorius, E., et al. 2018. The potential of LPS-binding protein to reverse amyloid format...
Type 2 diabetes (T2D) has many cardiovascular complications, including a thrombotic propensity. Many...
CITATION: De Waal, G. M., et al. 2018. Correlative Light-Electron Microscopy detects lipopolysacchar...
Many chronic diseases, including those classified as cardiovascular, neurodegenerative, or autoimmun...
Parkinson’s disease is a neurological disease that affects approximately 3% of the population over ...
There is great interest in developing reproducible high-throughput screens to identify small molecul...
Parkinson's disease (PD) is a well-known neurodegenerative disease with a strong association establi...
INTRODUCTION: Lipopolysaccharide (LPS) is the outer membrane component of Gram-negative bacteria. LP...
Parkinson’s disease (PD) is one of the most common neurodegenerative movement disorders which is cha...
<p><b>A and B)</b> Clot structure from two healthy individuals, imaged in an SEM and showing a ‘norm...
The thrombin-induced polymerisation of fibrinogen to form fibrin is well established as a late stag...
The thrombin-induced polymerisation of fibrinogen to form fibrin is well established as a late stage...
Dataset for paper. ALSO see link to raw figure data files stored at the following link:<div><br></d...
Many studies indicate that there is a (mainly dormant) microbial component in the progressive develo...
CITATION: Pretorius, E., Mbotwe, S. & Kell, D. B. 2017. Lipopolysaccharide-binding protein (LBP) rev...
CITATION: Pretorius, E., et al. 2018. The potential of LPS-binding protein to reverse amyloid format...
Type 2 diabetes (T2D) has many cardiovascular complications, including a thrombotic propensity. Many...
CITATION: De Waal, G. M., et al. 2018. Correlative Light-Electron Microscopy detects lipopolysacchar...
Many chronic diseases, including those classified as cardiovascular, neurodegenerative, or autoimmun...
Parkinson’s disease is a neurological disease that affects approximately 3% of the population over ...
There is great interest in developing reproducible high-throughput screens to identify small molecul...
Parkinson's disease (PD) is a well-known neurodegenerative disease with a strong association establi...
INTRODUCTION: Lipopolysaccharide (LPS) is the outer membrane component of Gram-negative bacteria. LP...
Parkinson’s disease (PD) is one of the most common neurodegenerative movement disorders which is cha...