Dendogram and heatmap representation of unsupervised hierarchical clustering (HCA) of the metabonome for all children sorted according to the villus height (VH).

<p>Each column corresponds to a single children and each row corresponds to a specific metabolites. Only metabolites identified to correlate with VH through and OPLS model were used for metabolite clustering. Metabolite z-score transformation was performed on the levels of each metabolite across samples, with blue denotating a lower and red a higher level compared to the mean. Metabolites were clustered using correlation distance and average linkage. DMA, dimethylamine; 2-HIB, 2−hydroxyisobutyrate; 4-HPP, 4-hydroxypurate; 4-HPA, 4-hydroxyphenylacetate; 3-IS, 3−indoxyl sulfate; NAG, N-acetylglycoprotein; PAG, phenylacetylglutamine; TMA, trimethylamine.